Tottenham will face Sydney FC in a friendly at the ANZ Stadium on May 30.
Spurs were invited by the New South Wales government and Destination South Wales to take part in a week of sporting events in the city.
Manager Mauricio Pochettino said: "We are looking forward to visiting Sydney and giving our fans in that part of the world an opportunity to see the team up close.
"We all appreciate the fantastic support we receive across the world and the commitment that people in different time zones make to watch games live on TV, so to bring the team to them is a great way to say thank you."