Manchester United are to relocate 2,600 season ticket holders -- including 800 by the start of next season -- to help create 300 new places for fans with disabilities.
Premier League clubs have already been made aware that they face heavy fines and even points deductions if they fail to meet an August deadline to become compliant with disability access requirements, according to a report by the Culture, Media and Sport select committee.
United say "all structural work will be completed ahead of the 2017-18 campaign" and confirmed their plans on Tuesday morning. Season ticket holders who are affected by the change will be relocated over three years.
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The current East Stand accessible platform will be extended across and into the Sir Alex Ferguson and Sir Bobby Charlton Stands, and new amenity seating will also be added in these areas.
United are set to cover the cost of relocating fans, should they have to take up more expensive seats, and provide free tickets to all cup ties played at Old Trafford for a year as part of a goodwill package.
Chas Banks, secretary of the Manchester United Disabled Supporters' Association (MUDSA), said: "I'm filled with pride that the club I've supported since first coming to Old Trafford as a little boy in 1957, is leading the way in increasing accessible seating to meet the standards set out in the Accessible Stadia guide. It's a dream come true for me and many other disabled United fans.
"This is a huge task and it can't be completed overnight. However, it will be completed faster than most believed possible. More importantly, this expansion is the beginning of a process, not the end. Manchester United is constantly looking to improve in every area and I'm confident they will apply that same ambition towards their disabled fans.
"Finally, on behalf of all the disabled members, I'd like to send my sincere thanks to all of our fellow fans who have to move to allow this expansion to happen. Without your cooperation, our dream couldn't come true and we thank you for your help and patience."
United managing director Richard Arnold is proud that he will soon be welcoming more disabled fans. Arnold confirmed Old Trafford's overall capacity will be reduced from 75,643 to between "72,500 and 73,000" as a result of changes he is proud to help implement.
"We're really pleased to be able to announce the provision of the facilities in time for the start of next season," he told PA Sport. "To have the compliant number of spaces available is a great achievement and something we not only believe was the right thing to do, but are proud to be able to be provide to the disabled community."
Asked about the financial hit of the changes, the United managing director said: "Money hasn't been a factor in looking at this issue. It is something we felt was the right thing to do. We wanted to make sure we were compliant for the start of next season and we wanted to make sure that we did this in a way that was sensitive to the existing fans in those seats.
"I think what you'll see is that it underlines that commitment we've made to the disabled community over the last 25 years."
Arnold says the relocation of supporters has "weighed very heavily" on their mind and is behind United's three-year phased programme.
The Manchester United Supporters Trust has called for the club to extend the one-year price freeze to the 2,600 relocated as "no supporter who is compulsorily relocated should suffer any financial loss." The trust also said it will be making a "strenuous argument" for the general expansion of Old Trafford, not only reclaiming the lost seats but making the ground's capacity "the largest in Europe."
Level Playing Field -- a charity promoting good access for all fans and one of the stakeholders United worked with -- expressed disappointment that United chose a phased plan that could extend to 2020 rather than making all the changes at once.
Information from the Press Association was used in this report.