Inter Milan duo Ivan Perisic and Mauro Icardi will not be available for their side's Serie A game against Genoa on Saturday.
Perisic, who was a target of Manchester United last summer, has a reported shoulder injury.
Leading scorer Icardi, who has missed Inter's past two matches, remains out due to a muscular injury.
"Icardi and Perisic are players we always want to have in the group," manager Luciano Spalletti said to a news conference.
"We did some tests but they hadn't recovered enough in training to feature in a match with the tempo of Genoa-Inter."