Borussia Dortmund put some pressure on Bayern Munich at the top of the Bundesliga with a convincing 5-1 win at Wolfsburg.
Pierre-Emerick Aubameyang was on target twice for the Westphalians, with Raphael Guerreiro, Ousmane Dembele and Lukasz Piszczek also finding the back of the net for Thomas Tuchel's men.
Daniel Didavi scored what proved to be merely a consolation for Wolfsburg, for whom Mario Gomez drew a blank for the third game in a row since arriving from Fiorentina.
Former Barcelona player Marc Bartra left the match early in the first half with an apparent injury and is a doubt to be ready to face Real Madrid next week in the Champions League.
Freiburg put the pressure on Hamburg's under-fire coach Bruno Labbadia with a 1-0 win at the Dreisamstadion.
Nils Petersen's 70th-minute strike was enough to take Christian Streich's men into the top half of the table and leave their northern Germany rivals inside the bottom three with just one point from their first four games of the season.
Bobby Wood hit the post for Hamburg, but their lack of a reaction in the second half may worry club bosses. The pressure is already high on Labbadia, who may become the second Bundesliga coaching casualty this season following the dismissal of Viktor Skripnik at rivals Werder Bremen at the weekend.
Hamburg have just one point from their first four games of the season and could drop into the bottom two on Wednesday.
Eintracht Frankfurt moved into a share of top spot in the table thanks to a 2-0 win over winless Ingolstadt.
Goals either side of half-time from David Abraham and Bastian Oczipka did the damage at the Audi-Sportpark and lifted last season's relegation playoff participants into fourth place, behind Borussia Dortmund, Bayern Munich and Hertha Berlin only on goal difference.
Lukas Hradecky had a slightly busier second half in the Frankfurt goal, but Ingolstadt were unable to find a route back into the game as they succumbed to their third defeat in four games this season.
Hoffenheim had to settle for their fourth successive draw this season after Darmstadt netted a last-gasp leveller to salvage a 1-1 draw at the Bollenfalltorstadion.
Andrej Kramaric's goal just after half-time had put the visitors in front and that seemed like it would be enough to earn Julian Nagelsmann's men their first victory of the season.
However, Darmstadt hit back right at the death to snatch a point and ensure they remained level on points with Hoffenheim.
Denys Oliynyk was Darmstadt's hero, turning in fellow substitute Sandro Sirigu's cross unmarked at the far post with the last kick of the game.