Jose Mourinho returns to face Chelsea, Manchester City's Southampton test
Jose Mourinho returns to former club Chelsea with Manchester United on Sunday having struggled to break down Liverpool in the 0-0 draw at Anfield, but seeing his side score four against Feyenoord.
Arsenal are flying high after their demolition of Ludogorets, which was their seventh win in a row in all competitions, and will hope add to that streak against struggling Middlesbrough, while leaders Manchester City take on Southampton hoping to get back on track after their humbling at Barcelona.
Will David Moyes finally win a game as Sunderland boss? And can Everton to push for a place among the big boys at the top of the table?
Predict the Premier League matches in ESPN FC's polls.
CHELSEA: Jose Mourinho will be out to prove a point on his return to Stamford Bridge and come away with all three with Manchester United. Equally, Antonio Conte will want to reinforce the growing belief that he is a worthy long-term successor to the Special One. A tight game looks in prospect with a draw the likely outcome.
Prediction: Chelsea 1-1 Manchester United -- Mark Worrall
MAN UNITED: Chelsea have been impressive when dispatching teams with far fewer resources, but have struggled to overcome their traditional rivals. Meanwhile, Jose Mourinho's team are still struggling for attacking cohesion of their own, and so his homecoming - which may be a little acrimonious - looks set to be a stalemate.
Prediction: Chelsea 1-1 Manchester United -- Musa Okwonga
MAN CITY: With a 10-win start morphing into a run of two defeats and two draws, City need three points quickly to quell growing nerves. Having delivered many of their own problems in Barcelona, a clean sheet and goals from a restored Sergio Aguero (maybe even a penalty) would be welcome vs. Southampton.
Prediction: Manchester City 3-1 Southampton -- Simon Curtis
SOUTHAMPTON: A tough week does not get any easier as Southampton travels to the Etihad hot on the heels of a 1-0 Europa League defeat against Italian giants Inter Milan. Goalkeeper Fraser Forster may need to be on top form to keep out City's potent attack.
Prediction: Manchester City 2-1 Southampton -- Alex Crook
BOURNEMOUTH: After Bournemouth's outstanding 6-1 win over Hull at the weekend, the Cherries will be as confident as ever in continuing their home form against Tottenham. Spurs are without key men Harry Kane and Toby Alderweireld, which also works in the home side's favour. The Cherries will win again with Josh King netting late on.
Prediction: Bournemouth 2-1 Tottenham -- Will Kent
TOTTENHAM: Bournemouth will be on a high after their 6-1 thrashing of Hull, while Spurs will be reflecting on the lack of clinical finishing in front of goal that cost them dear against both West Brom and Leverkusen. But these are the games any side that considers themselves to be title contenders should be expecting to win, and Mauricio Pochettino is likely to ring the changes to get the job done.
Prediction: Bournemouth 1-2 Tottenham -- John Crace
ARSENAL: The 6-0 win over Ludogorets was their ninth from their last 10 games, and the fact that the goals are being spread around means Arsene Wenger's side are difficult to defend against. With chief creator Mesut Ozil now turned regular goalscorer, the unpredictability means opposition can't plan as well as they have been able to in the past. The only issue might be fatigue, but the Gunners look as if they have the squad depth to cope with that.
Prediction: Arsenal 2-0 Middlesbrough -- Andrew Mangan
MIDDLESBROUGH: It's a big ask for Middlesbrough to pick themselves up from a demoralising and hugely disappointing 1-0 defeat at home to Watford. A trip to the Emirates is less than ideal but Boro will hope that at least some faith and character shine through in an attempt to turn things around.
Prediction: Arsenal 4-0 Middlesbrough -- Catherine Wilson
LIVERPOOL: Having already witnessed the restrictive tactics of Manchester United, Liverpool fans must hope their team will be better prepared for similar measures from Tony Pulis' West Brom. Pressure is building for the Reds to shine in every game now but a tight match will be expected with few chances.
Prediction: Liverpool 1-0 West Brom -- Stephen Kelly
WEST BROM: The Baggies head to Liverpool for the second of three consecutive fixtures against teams in the top four of the Premier League. With key man Jonny Evans suspended, West Brom stalwart Jonas Olsson will step in as Tony Pulis' side look to nullify Liverpool's exciting front three.
Prediction: Liverpool 2-0 West Brom -- Matthew Evans
LEICESTER: The Foxes will hope to continue in Champions League form. Leicester have been practically two different sides in the Premier League and Europe thus far. The 1-0 home win last season over the Eagles was City's first clean sheet of the campaign and earned a pizza reward from manager Claudio Ranieri. If Leicester can defend equally as well as that day they will win comfortably.
Prediction: Leicester 2-0 Crystal Palace -- Ben Jacobs
CRYSTAL PALACE: The Eagles are difficult opposition when playing away, and with Leicester City going through a patchy spell in the league, the opportunity is there for Alan Pardew's side to take advantage. So long as the service to Christian Benteke is there, Palace have a great chance of collecting three points.
Prediction: Leicester 1-2 Crystal Palace -- Rob Sutherland
BURNLEY: The hosts are expected to be without key midfielder Steven Defour due to a hamstring injury and star striker Andre Gray serves the last game of a four-match ban. The Clarets have been strong at home this season, but the pace and movement of Everton's attack will cause them problems and a third straight league loss feels likely.
Prediction: Burnley 1-2 Everton -- Jamie Smith
EVERTON: After their defensive capabilities earned a point against free-scoring Manchester City, Everton travel to Burnley in search of the right balance in the final third as only an in-form Romelu Lukaku is showing the necessary consistency at present. The Blues need to end a three-game winless run in the league.
Prediction: Burnley 0-2 Everton Luke O'Farrell
WEST HAM: The Hammers will view a home game against Sunderland as a chance to build on last week's win against Crystal Palace. Team confidence is up and fans are looking forward to laying to rest some of the myths about their new London Stadium.
Prediction: West Ham 3-0 Sunderland -- Peter Thorne
SUNDERLAND: West Ham started the season badly but are in better spirits after a win at Crystal Palace, while Sunderland still look incapable of more than an occasional draw. Only a supreme effort from David Moyes' uninspiring and injury-ravaged squad will take anything from this game; a sound defeat seems more likely.
Prediction: West Ham 3-0 Sunderland -- Colin Randall
SWANSEA: Bob Bradley helped Swansea rediscover their scoring touch last Saturday against a strong Arsenal side. This weekend they will face Watford, who can't match Arsenal's firepower and don't have as good of a defence, as Bradley makes his home Premier League debut. This must be the moment Swansea turn their season around.
Prediction: Swansea 3-1 Watford -- Max Hicks
WATFORD: After coming out on top in a turgid affair against Middlesbrough, Watford will be hopeful of taking another three points from another struggling side. Although not tested at the Riverside, the defence still looks creaky and is particularly vulnerable to set pieces. At the other end of the pitch, Isaac Success is quickly making a name for himself and the Swansea back line won't be relishing their afternoon against him and Troy Deeney.
Prediction: Swansea 1-2 Watford -- Mike Parkin
HULL CITY: Two months after their last Premier League win, Hull can look forward to their first inviting home fixture of the season against Stoke, an opponent they have already beaten in the EFL Cup. Hope, though, is tempered by last weekend's thumping defeat at Bournemouth and the loss of the club's only senior left-back, Andy Robertson, to a long-term injury. A point might not be such a bad result, if only to stop the rot.
Prediction: Hull 1-1 Stoke -- Phil Buckingham
STOKE: Unlikely goal-machine Joe Allen will be licking his lips at the prospect of facing a Hull defence that conceded six goals in their last game. With any luck he will be joined on the scoresheet by an ever-improving Wilfried Bony who is yet to score a goal this calendar year. Hull 0-2 Stoke.
Prediction: Stoke 2-0 Hull -- James Whittaker
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