Copa America 2015 hosts Chile, and CONMEBOL's top-two ranked teams, Brazil and Argentina, got the No. 1 seeds in their respective groups on Monday in the draw held in Vina Del Mar, Chile.
Chile are joined in Group A by Mexico, Ecuador and Bolivia, while defending champions Uruguay are the two-seed in Group B along with No. 1 Argentina, then Paraguay and Jamaica rounding out that group.
Brazil are the top seed in Group C, and are matched with Colombia, Peru and Venezuela.
All 10 members of the South American confederation are guaranteed spots in the tournament, while two teams -- Jamaica and Mexico this time around -- are invited to participate as guests.
The Chileans will be trying to win the Copa America for the first time.
"Hopefully this time we will be able to play up to the expectations," Chile coach Jorge Sampaoli said.
The top two teams in each of the three groups will advance to the competition's quarterfinals, along with the best two third-place finishers.
Brazil and Colombia will play in a rematch of the World Cup quarterfinals, when the hosts won 2-1 in a match marked by Neymar's back injury that ruled him out of the competition.
While Brazil is trying to rebuild under new coach Dunga, Colombia has been thriving under Jose Pekerman and Real Madrid star James Rodriguez.
"We are getting used to playing against Brazil," Pekerman said. "Hopefully we will be able to win this time."
Lionel Messi's Argentina will have to face Uruguay, the same team it lost to in the quarterfinals when they hosted the tournament in 2011.
Uruguay is the competition's most successful nation with 15 titles, but it won't be able to count on Barcelona star striker Luis Suarez, who will still be serving FIFA's suspension for biting an opponent during the World Cup.
The 12-nation tournament will be played in eight host cities -- Antofagasta, Concepcion, La Serena, Rancagua, Santiago, Temuco, Valparaiso and Vina del Mar.