Udinese ended Sampdoria's unbeaten Serie A start with a 4-0 victory at Friuli, where Blucerchiati midfielder Edgar Barreto was sent off.
The home side had been on the back of a three-match losing streak, but went ahead on 27 minutes through a penalty from Rodrigo De Paul.
Sampdoria, who beat AC Milan last time out, then found themselves down to 10 men after Barreto collected his second caution just before the break.
Udinese doubled their lead after 66 minutes from another penalty, this time Maxi...
Stephan El Shaarawy scored twice as Roma continued their fine form with a 3-1 win against Udinese in Serie A.
The Italy forward scored twice in the first half as Roma made it three straight wins and handed Udinese a third successive defeat.
It took Roma 12 minutes to break the deadlock. Radja Nainggolan lost his footing on the edge of the area but was still able to poke the ball through to Edin Dzeko, who calmly slotted in low to Albano Bizzarri's right for his fifth goal in three games.
Nikola Kalinic was denied a hat trick on review as AC Milan beat Udinese 2-1 to bounce back from last weekend's 4-1 mauling by Lazio.
Kalinic thought he had scored a third goal eight minutes from time but it was ruled out for offside through VAR.
Udinese also had a goal for Kevin Lasagna ruled out by the video assistant referee early on.
Lasagna did eventually get on the scoresheet, with the equaliser, between Kalinic's goals, his first for Milan since joining from Fiorentina.