Chelsea were without the in-form forward Eden Hazard for Saturday 2-1 win at Stoke City after he picked up an injury in training.
Hazard, 26, did not travel with the rest of the squad as Gary Cahill scored an 87th-minute winner at the bet365 stadium.
"In the last training he felt a bit of a problem in his calf, for this reason I decided not to risk him," manager Antonio Conte said. "That is why he didn't play today."
The muscle injury makes him a doubt for Belgium's upcoming internationals -- a World Cup qualifier at home to Greece and a friendly against Russia.
Chelsea's next game is at home to Crystal Palace on Saturday, April 1.