Swansea are set to rest several first-team players for the Capital One Cup visit of Rotherham on Tuesday night.
Boss Garry Monk could give a break to the likes of skipper Ashley Williams, Angel Rangel, Lukasz Fabianski and Wilfried Bony for the clash at the Liberty Stadium.
Instead, Monk could hand debuts to new boys Federico Fernandez, the B£8million centre-half signed from Napoli, and midfielder Tom Carroll, who has joined on a season-long loan from Tottenham.
Captain Williams is hoping the club can build on a perfect start to the season by keeping star striker Bony.
Monk's men made it two wins out of two on Saturday by backing up the shock opening-day win at Manchester United with a 1-0 home victory over newly-promoted Burnley.
Monk added to his squad last week by signing defender Fernandez and Spurs midfielder Carroll on a season-long loan deal, but it is the potential loss of key personnel which Williams is concerned about after putting six points on the board.
Bony has been linked with Liverpool and Tottenham after his goal-scoring exploits in the Premier League last season and for the Ivory Coast at the World Cup in Brazil - and Williams knows the importance of keeping the muscular 25-year-old frontman beyond the September 1 transfer deadline.
"It's not for me to say who comes in, but I don't want to lose anyone," said the Wales defender after celebrating his 30th birthday with a first home victory of the season.
"I think we have got a lot of talent at the moment with depth on the bench and the more quality players we have in our squad, the better.
"Bony looked the best I have seen him in pre-season. He is hungry and disappointed when he doesn't score.
"We are really glad to have him, especially after the speculation about him. It just shows how important he is to our team.
"I feel good about the squad, there are some good personalities and the talent in the team is really good.
"Off the field too, everyone is part of a really tight unit. I think we have brought in quality and I like the way it looks when I am at training."
Rotherham boss Steve Evans is expected to rotate his squad with Febian Brandy poised to make his debut following a muscular injury.
Defender Joe Skarz faces a late fitness test following his collision with Millwall goalkeeper Adam Collin at the weekend.
Striker Matt Derbyshire is hoping to return to the starting line-up, but midfielders Paul Green and Rob Milsom (both ankle), plus defender Frazer Richardson (foot) remain sidelined.
Ryan Hall (ankle) could return to contention. He has missed the Millers' last two games after scoring the winner in the recent victory against Wolves.