Manchester United midfielder Marouane Fellaini and Chelsea goalkeeper Thibaut Courtois will miss Belgium's friendly against Russia on Tuesday with injuries.
Fellaini suffered a toe problem and Courtois sustained a hip injury in the 1-1 World Cup qualifying draw with Greece in Brussels on Saturday.
Courtois played the full 90 minutes but Fellaini came off shortly after the hour mark.
His Chelsea teammate Eden Hazard, Manchester City's Kevin De Bruyne and Paris Saint-Germain defender Thomas Meunier had already been ruled out of both games.
Montreal Impact defender Laurent Ciman picked up a knee injury in the match in Brussels, and will also miss the trip to Sochi to face the 2018 World Cup hosts Russia.